|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide CTVYRGDKSQASRPT conjugated to KLH, corresponding to amino acids 65-79 of Human Ogg 1.|
|Purification||Antigen affinity chromatography|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA1-31402 detects Ogg1 from human, mouse, and rat samples.
PA1-31402 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue), Western blot applications.
The PA1-31402 immunogen is: Synthetic peptide: CTVYRGDKSQASRPT conjugated to KLH, corresponding to amino acids 65-79 of Human Ogg 1.
8-hydroxyguanine, a form of oxidative DNA damage induced by free radicals, causes G:C to T:A transversion. In E. Coli, three DNA repair enzymes exist to prevent the mutagenic effects of 8-hydroxyguanine. One of these enzymes, MutM, was found to have a f
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.
PA1-31402 was used in western blot to analyze an accessory factor protein in oxidative DNA damage repair called CUX2
|Pal R,Ramdzan ZM,Kaur S,Duquette PM,Marcotte R,Leduy L,Davoudi S,Lamarche-Vane N,Iulianella A,Nepveu A||The Journal of biological chemistry (290:22520)||2015|