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Invitrogen
Omega-hexatoxin-Hv1a Polyclonal Antibody
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Omega-hexatoxin-Hv1a Antibody (PA5-144389) in WB
Western blot analysis of Omega-hexatoxin-Hv1a in recombinant protein using a dilution of 1:2,000. Samples were incubated with Omega-hexatoxin-Hv1a polyclonal antibody (Product # PA5-144389). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 25 kDa. Observed band size: 25 kDa.
Product Details
PA5-144389
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Arthropod
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa )
Conjugate
Form
Liquid
Concentration
4 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons (PubMed:17610847). Is lethal to many insect species but not toxic to mammals (PubMed:9228949, PubMed:16779650). May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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