In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human OSM is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.
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Protein Aliases: MGC20461; Oncostatin-M; OSM
Gene Aliases: OncoM; Osm
UniProt ID: (Mouse) P53347
Entrez Gene ID: (Mouse) 18413