|Tested species reactivity||Chicken, Human, Mouse, Pig, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 500-600 of human Opa1.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||2.5 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||2.5 µg/ml|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody shares 100% sequence homology with primate, 94% with zebrafish.
Suggested positive control: human brain protein.
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice.
PA1-16991 was used in western blot to use diabetic mice fed a high-fat diet to study disease-related changes in mitochondrial function and proteomics
|Guo Y,Darshi M,Ma Y,Perkins GA,Shen Z,Haushalter KJ,Saito R,Chen A,Lee YS,Patel HH,Briggs SP,Ellisman MH,Olefsky JM,Taylor SS||Molecular and cellular proteomics : MCP (12:3744)||2013|