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Opsin 3 (extracellular) Antibody (AOR-023-200UL) in IHC (F)
Expression of Opsin 3 in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Opsin 3 (extracellular) Antibody (#AOR-023) (1:300), followed by goat anti-rabbit-AlexaFluor-488. A. Staining in the CA3 region, showed Opsin 3 immunoreactivity (green), in the pyramidal layer (P, left pointing arrows) and in the mossy fiber terminal zone (MFT, right pointing arr... View More
Product Details
AOR-023-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide CRPIYEFHGLYEEK, corresponding to amino acid residues 270-283 of human P2X1 receptor. Extracellular loop.
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: CRPIYEFHGLYEEK
Reconstitution: 50 uL double distilled water (DDW). The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. May play a role in encephalic photoreception. Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Encephalopsin; NMO-1; opsin (encephalopsin); opsin 3 (encephalopsin, panopsin); Opsin-3; Panopsin; protein phosphatase 1, regulatory subunit 116
Gene Aliases: ECPN; ERO; OPN3; PPP1R116
UniProt ID: (Human) Q9H1Y3, (Mouse) Q9WUK7
Entrez Gene ID: (Human) 23596, (Rat) 498289, (Mouse) 13603
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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