Immunogen sequence: ILNILFFCLL LPTAVIVFSY VKIIAKVKSS SKEVAHFDSR IHSSHVLEMK LTKVAMLICA GFLIAWIPYA VVSVWSAFGR PDSIPIQLSV VPTLLAKSAA M; Positive Samples: U-251MG, HeLa, Mouse eye, Mouse brain, Mouse testis, Rat eye, Rat brain; Cellular Location: Membrane, Multi-pass membrane protein
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this gene may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants encoding different isoforms. Detected in the eye, testis, brain, retina and cell lines derived from neural retina.
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Protein Aliases: DJ402H5.1; G protein-coupled receptor 136; G-protein coupled receptor 136; G-protein coupled receptor PGR12; Neuropsin; Opsin-5; Transmembrane protein 13
Gene Aliases: GPR136; GRP136; Neuropsin; OPN5; PGR12; TMEM13
Molecular Function: G-protein coupled receptor