This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
This antibody is predicted to react with Monkey, Horse, cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Optineurin (OPTN) plays an important role in the maintenance of the Golgi complex, membrane trafficking, and exocytosis. It functions through its interaction with myosin VI and Rab8. Optineurin links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. It also plays a role in the activation of innate immune response during viral infection. Mutations affecting this gene are associated with Gluacoma 1 (GLC1E).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 14.7K-interacting protein 2; E3-14.7K-interacting protein; FIP-2; FIP-2-like protein; FIP2; HIP-7; Huntingtin interacting protein L; Huntingtin yeast partner L; Huntingtin-interacting protein 7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Optineurin; TFIIIA-INTP; Transcription factor IIIA-interacting protein; transcrption factor IIIA-interacting protein; tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; GLC1E; HIP7; HYPL; NRP
Gene Aliases: 4930441O07Rik; ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; OPTN; TFIIIA-INTP