Invitrogen

Osteocalcin Monoclonal Antibody (2H9F11F8)

Product Details

MA1-82975

Applications	Tested Dilution	Publications
Immunohistochemistry (IHC)	-	View 1 publication 1 publication
Immunocytochemistry (ICC/IF)	-	View 1 publication 1 publication
ELISA (ELISA)	Assay-dependent	-

Product Specifications
Species Reactivity	Bovine, Human, Pig, Rabbit, Rat
Published species	Rat
Host/Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Clone	2H9F11F8
Immunogen	Recombinant human osteocalcin GST fusion protein
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Protein A
Storage buffer	PBS
Contains	0.09% sodium azide
Storage conditions	4°C or -20°C if preferred
RRID	AB_2064889

Product Specific Information

This antibody does not cross-react with mouse Osteocalcin.

Mouse anti Human Osteocalcin antibody, clone 2H9F11F8 recognizes intact human and bovine osteocalcin in a ""2 site"" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule.

Target Information

Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Polymeric nanofibrous scaffolds laden with cell-derived extracellular matrix for bone regeneration.

Materials science & engineering. C, Materials for biological applications

Junka R,Yu X

MA1-82975 was used in Immunohistochemistry to demonstrate the potential to fabricate tailored biomimetic grafts with dECM cues and fibrous architecture for bone applications.

Sat Aug 01 00:00:00 EDT 2020

Acellular polycaprolactone scaffolds laden with fibroblast/endothelial cell-derived extracellular matrix for bone regeneration.

Journal of biomedical materials research. Part A

Junka R,Quevada K,Yu X

MA1-82975 was used in Immunocytochemistry to investigate if osteoconduction of deposition of decellularized extracellular matrix can be tailored with the appropriate combination of cells to accelerate osteoblast mineral secretion.

Sat Feb 01 00:00:00 EST 2020

Bioinformatics

Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin); Bone Gla protein; bone gla protein BGP; bone Gla-protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; PMF1; RP11-54H19.5; unnamed protein product

Gene Aliases: BGLAP; Bglap2; BGP; Bgpr; Bgpra; OC; OCN

UniProt ID: (Human) P02818, (Bovine) P02820, (Rat) P04640

Entrez Gene ID: (Human) 632, (Bovine) 281646, (Rabbit) 100340503, (Pig) 397530, (Rat) 25295

Function(s)