Invitrogen

Osteocalcin Monoclonal Antibody (5021)

Product Details

Tested Applications

Dilution

ELISA (ELISA)

5-10 µg/mL

Immunohistochemistry (IHC)

5-10 µg/mL

Radioimmune Assays (RIA)

5-10 µg/mL

Western Blot (WB)

5-10 µg/mL

Product Specifications

Species Reactivity

Bovine, Human

Host / Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5021

Immunogen

Bone osteocalcin.

Conjugate

Unconjugated

Form

Liquid

Concentration

5.7 mg/mL

Purification

Ammonium sulfate precipitation, Ion-exchange chromatography

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2065191

Product Specific Information

MA1-43028 detects Osteocalcin in human and bovine samples.

MA1-43028 has successfully been used in radioimmunoassays, western blot, ELISA and immunohistochemistry applications. Immunohistochemistry is calcium dependent.

MA1-43028 was derived from human bone osteocalcin.

Target Information

Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: BGLAP; BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin

Gene Aliases: BGLAP; BGP; BOS_2768; OC; OCN

UniProt ID: (Human) P02818, (Bovine) P02820

Entrez Gene ID: (Human) 632, (Bovine) 281646

Molecular Function: calcium-binding protein extracellular matrix protein