MA1-25584 detects Osteocalcin from human, rat, bovine, canine, goat, porcine, rabbit, and ovine samples. MA1-25584 will not react with mouse.
MA1-25584 has been successfully used in immunohistochemistry (frozen / paraffin) and Western blot procedures.
The MA1-25584 immunogen is full length bovine protein. This antibody detects an epitope corresponding to residues 21-31 of bovine Osteocalcin.
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate (gla) protein-like; bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamate protein osteocalcin; bone gamma-carboxyglutamate; BGLAP; bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin); Bone Gla protein; bone Gla-protein; gamma-carbooxyglutamate (gla) protein; Gamma-carboxyglutamic acid-containing protein; OC; Osteocalcin; PMF1; RP11-54H19.5
Gene Aliases: BGLAP; Bglap2; BGP; Bgpr; Bgpra; BOS_2768; GLA; OC; OCN