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|Tested species reactivity||Mouse, Rat|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from the intracellular C-terminal region of the human P2Y1 receptor protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
||P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2.||Fam SR,Paquet M,Castleberry AM,Oller H,Lee CJ,Traynelis SF,Smith Y,Yun CC,Hall RA||Proceedings of the National Academy of Sciences of the United States of America (102:8042)||2005|
|Human||Not Cited||P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2.||Fam SR,Paquet M,Castleberry AM,Oller H,Lee CJ,Traynelis SF,Smith Y,Yun CC,Hall RA||Proceedings of the National Academy of Sciences of the United States of America (102:8042)||2005|
ATP receptor; p2 purinoceptor subtype Y1; P2 purinoreceptor subclass 2Y; P2RY1; P2Y ATP receptor 1; P2Y purinoceptor 1; p2y-1-r; p2Y1; P2Y1 receptor; p2y1r; Platelet ADP receptor; Purinoceptor p2y1; Purinoceptor p2yr1
P2ry1; P2y; P2Y1