PA1-21872 detects AXUD1 in human samples.
PA1-21872 has been successfully used in Western blot procedures.
PA1-21872 immunogen is AXUD1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs) and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD 1 (AXIN 1 up-regulated), has enhanced expression in response to exogenously expressed AXIN 1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD 1 may have a tumor-supressor function in those organs.
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Protein Aliases: Axin-1 up-regulated gene 1 protein; AXIN1 up-regulated 1; AXUD1; CSRNP-1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; FAM130B; Protein URAX1; TAIP-3; TGF-beta-induced apoptosis protein 3; URAX1
Gene Aliases: AXUD1; CSRNP-1; CSRNP1; FAM130B; TAIP-3; TAIP3; URAX1
UniProt ID: (Human) Q96S65
Entrez Gene ID: (Human) 64651