This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cytoplasmic phosphoprotein PACSIN2; Protein kinase C and casein kinase substrate in neurons 2 protein; Protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; SdpIIsyndapin II; Synaptic dynamin-associated protein II; syndapin 2; Syndapin II; Syndapin-2; Syndapin-II; syndapin2; x-PACSIN2
Gene Aliases: AI197433; PACSIN2; SDPII; XELAEV_18019736mg