PA1-4237 detects Kallikrein-12 from human samples.
PA1-4237 has been successfully used in Western blot procedures.
PA1-4237 immunizing peptide corresponds to amino acid residues 236-248 from human Kallikrein-12.
Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. A novel KLK gene, KLK12, is expressed in a variety of tissues including salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, breast, thyroid, and trachea. It has applications as a novel cancer biomarker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: kallikrein 12; Kallikrein-12; Kallikrein-like protein 5; kallikrein-related peptidase 12; KLK-12; KLK-L5
Gene Aliases: KLK-L5; KLK12; KLKL5; UNQ669/PRO1303
UniProt ID: (Human) Q9UKR0
Entrez Gene ID: (Human) 43849
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule