Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL36 encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p.
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Protein Aliases: 39S ribosomal protein L36, mitochondrial; BRCA1-interacting protein 1; L36mt; Mitochondrial large ribosomal subunit protein bL36m; MRP-L36; putative BRCA1-interacting protein
Gene Aliases: AI646041; BRIP1; L36mt; MRP-L36; MRPL36; PRPL36; RPMJ