HtrA1 a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.
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Protein Aliases: High-temperature requirement A serine peptidase 1; IGFBP5-protease; insulin-like growth factor binding protein 5 protease; L56; protease, serine, 11 (IGF binding); Serine protease 11; Serine protease HTRA1
Gene Aliases: AI429470; ARMD7; CADASIL2; CARASIL; HTRA; HTRA1; L56; ORF480; PRSS11; RSPP11