This antibody is predicted to react with rat based on sequence homology.
LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Protein Aliases: Keratan sulfate proteoglycan lumican; KSPG lumican; Lumican; Lumican precursor; lumican proteoglycan
Gene Aliases: Lcn; LDC; LUM; SLRR2D