This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. View Details
It is not recommended to aliquot this antibody.
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 53BP1; FLJ41424; MGC138366; p53-binding protein 1; TP53-binding protein 1; tumor protein 53-binding protein, 1; tumor protein p53-binding protein, 1
Gene Aliases: 53BP1; p202; p53BP1; TDRD30; TP53; TP53BP1
UniProt ID: (Human) Q12888
Entrez Gene ID: (Human) 7158