This antibody is predicted to react with mouse and rat based on sequence homology.
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
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Protein Aliases: ADH beta; ADH gamma; ADH, alpha subunit; ADH, beta subunit; ADH, gamma subunit; ADH1A; ADH1B; ADH1C; ADH3; alcohol dehydrogenase 1 (class I), alpha polypeptide; Alcohol dehydrogenase 1A; Alcohol dehydrogenase 1B; alcohol dehydrogenase 1B class I; Alcohol dehydrogenase 1C; alcohol dehydrogenase 1C class I; alcohol dehydrogenase 2; alcohol dehydrogenase 2 (class I), beta polypeptide; alcohol dehydrogenase 3 (class I), gamma polypeptide; alcohol dehydrogenase 3 class I; alcohol dehydrogenase IB; Alcohol dehydrogenase subunit alpha; Alcohol dehydrogenase subunit beta; Alcohol dehydrogenase subunit gamma; aldehyde reductase; class I alcohol dehydrogenase; epididymis secretory protein Li 117; gamma polypeptide dehydrogenase 2 class I; pan ADH
Gene Aliases: ADH1; ADH1A; ADH1B; ADH1C; ADH2; ADH3; HEL-S-117