This antibody is predicted to react with bovine and mouse based on sequence homology.
RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Carcinoma-associated protein HOJ-1; HoJ-1; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; Ras association domain-containing protein 8
Gene Aliases: C12orf2; HOJ1; RASSF8
UniProt ID: (Human) Q8NHQ8
Entrez Gene ID: (Human) 11228