Recommended positive controls: A431.
Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (82%), Xenopus laevis (80%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Argininosuccinate synthase; argininosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2
Gene Aliases: ASS; ASS1; CTLN1
UniProt ID: (Human) P00966
Entrez Gene ID: (Human) 445
Molecular Function: ligase