This antibody is predicted to react with bovine based on sequence homology.
ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.
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Protein Aliases: ADM; Adrenomedullin; AM; PAMP; preproadrenomedullin; Proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide
Gene Aliases: ADM; AM; PAMP