Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: H1299, HeLa, Molt-4, Raji.
Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 72; G-protein coupled receptor 72; G-protein coupled receptor 83; glucocorticoid induced receptor; Hcepto9; Jp05
Gene Aliases: GPR72; GPR83; JP05; KIAA1540
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