Recommended positive controls: A431, Jurkat.
Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (92%), Xenopus laevis (93%), Pig (100%), Rabbit (98%), Chicken (94%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The TCP1 eta gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: CCT-eta; chaperonin containing t-complex polypeptide 1, eta subunit; HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; T-complex protein 1 subunit eta; T-complex protein 1 subunit eta, N-terminally processed; TCP-1-eta
Gene Aliases: CCT7; CCTETA; CCTH; NIP7-1; TCP1ETA
UniProt ID: (Human) Q99832
Entrez Gene ID: (Human) 10574