Recommended positive controls: MCF-7.
Predicted reactivity: Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: CAG repeat protein 1; CAS-interacting zinc finger protein; expanded repeat domain, CAG/CTG 2; Nuclear matrix protein 4; Nuclear matrix transcription factor 4; Trinucleotide repeat-containing gene 1 protein; Zinc finger protein 384
Gene Aliases: CAGH1; CAGH1A; CIZ; ERDA2; NMP4; NP; TNRC1; ZNF384
UniProt ID: (Human) Q8TF68
Entrez Gene ID: (Human) 171017