PA5-27587 targets ZNF384 in WB applications and shows reactivity with Human samples.
The PA5-27587 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 144 of Human ZNF384.
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This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.
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Protein Aliases: CAG repeat protein 1; CAG/CTG 2; CAGH1; CAGH1A; CAS-interacting zinc finger protein; CIZ; ERDA2; expanded repeat domain; expanded repeat domain, CAG/CTG 2; NMP4; Nuclear matrix protein 4; Nuclear matrix transcription factor 4; TNRC1; Trinucleotide repeat-containing gene 1 protein; Zinc finger protein 384
Gene Aliases: CAGH1; CAGH1A; CIZ; ERDA2; NMP4; NP; TNRC1; ZNF384
UniProt ID: (Human) Q8TF68
Entrez Gene ID: (Human) 171017