PA5-27984 targets TEAD4 in IF and WB applications and shows reactivity with Human samples.
The PA5-27984 immunogen is recombinant fragment corresponding to a region within amino acids 126 and 416 of Human TEAD4.
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This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
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Protein Aliases: EFTR-2; hRTEF-1B; related transcription enhancer factor 1B; RTEF1; TCF13L1; TEA domain family member 4; TEAD-4; TEF-3; TEF3; TEFR-1; Transcription factor 13-like 1; Transcription factor RTEF-1; transcriptional enhancer factor 1-related; transcriptional enhancer factor 3; Transcriptional enhancer factor TEF-3
Gene Aliases: EFTR-2; hRTEF-1B; RTEF1; TCF13L1; TEAD4; TEF-3; TEF3; TEFR-1
UniProt ID: (Human) Q15561
Entrez Gene ID: (Human) 7004
Molecular Function: transcription factor