Recommended positive controls: 293T.
Predicted reactivity: Pig (88%), Rhesus Monkey (97%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hydroxymethylbilane hydrolyase; Hydroxymethylbilane hydrolyase [cyclizing]; UROIIIS; Uroporphyrinogen-III cosynthase; Uroporphyrinogen-III synthase
Gene Aliases: UROIIIS; UROS
UniProt ID: (Human) P10746
Entrez Gene ID: (Human) 7390
Molecular Function: hydrolase