Recommended positive controls: HeLa, HepG2.
Predicted reactivity: Mouse (99%), Rat (99%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
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Protein Aliases: Fragile X mental retardation syndrome-related protein 2; fragile X mental retardation, autosomal homolog 2; fragile X-mental retardation 1-like 2
Gene Aliases: FMR1L2; FXR2; FXR2P
UniProt ID: (Human) P51116
Entrez Gene ID: (Human) 9513