Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (94%), Rat (94%), Dog (98%), Chicken (90%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activation/proliferation-associated protein 1; caprin 1; Caprin-1; Cell cycle-associated protein 1; cytop; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; Membrane component chromosome 11 surface marker 1; membrane component, chromosome 11, surface marker 1; RNA granule protein 105
Gene Aliases: CAPRIN1; GPIAP1; GPIP137; GRIP137; M11S1; p137GPI; RNG105
UniProt ID: (Human) Q14444
Entrez Gene ID: (Human) 4076
Molecular Function: transporter