Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.\r
Predicted reactivity: Mouse (88%), Rat (87%), Bovine (91%).\r
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
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Protein Aliases: acetylcholine receptor; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); cholinergic receptor; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); Chrnb 1; nAChRB1
Gene Aliases: ACHRB; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; SCCMS
UniProt ID: (Human) P11230
Entrez Gene ID: (Human) 1140