Recommended positive controls: U87-MG, MCF-7.
Predicted reactivity: Mouse (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; IMMT antibody; MICOS complex subunit MIC60; mitochondrial inner membrane organizing system 2; Mitochondrial inner membrane protein; Mitofilin; motor protein; p87/89; p87/89 antibody; proliferation-inducing gene 4
Gene Aliases: HMP; IMMT; MIC60; MINOS2; P87; P87/89; P89; PIG4; PIG52
UniProt ID: (Human) Q16891
Entrez Gene ID: (Human) 10989