Recommended positive controls: 293T, human FBXL4-transfected 293T cells.
Predicted reactivity: Mouse (91%), Rat (90%), Pig (92%), Rhesus Monkey (96%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F-box and leucine-rich repeat protein 4; F-box protein FBL4/FBL5; F-box/LRR-repeat protein 4
Gene Aliases: FBL4; FBL5; FBXL4; MTDPS13
UniProt ID: (Human) Q9UKA2
Entrez Gene ID: (Human) 26235