Recommended positive controls: MCF-7.
Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (81%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; GDP/GTP exchange factor (GEF)-like protein; RCC1 and BTB domain-containing protein 1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1; RP11-185C18.1
Gene Aliases: CLLD7; CLLL7; E4.5; GLP; RCBTB1
UniProt ID: (Human) Q8NDN9
Entrez Gene ID: (Human) 55213