Recommended positive controls: Jurkat, Raji.
Predicted reactivity: Mouse (97%), Rat (96%), Zebrafish (82%), Xenopus laevis (82%), Chicken (92%), Rhesus Monkey (99%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PLEKHF2 may play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
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Protein Aliases: EAPF; Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains; PH and FYVE domain-containing protein 2; PH domain-containing family F member 2; Phafin-2; Phafin2; pleckstrin homology domain containing, family F (with FYVE domain) member 2; Pleckstrin homology domain-containing family F member 2; Zinc finger FYVE domain-containing protein 18
Gene Aliases: EAPF; PHAFIN2; PLEKHF2; ZFYVE18
UniProt ID: (Human) Q9H8W4
Entrez Gene ID: (Human) 79666