Recommended positive controls: Raji, NCI-H929, NIH-3T3.
Predicted reactivity: Mouse (91%), Rat (89%), Chicken (81%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inactive tubulin--tyrosine ligase-like protein 12; TTL domain protein; ttll12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12
Gene Aliases: BC055368; D430005B17; dJ526I14.2; KIAA0153; TTLL12