PA5-32217 targets EPCR in WB applications and shows reactivity with mouse and Human samples.
The PA5-32217 immunogen is recombinant fragment corresponding to a region within amino acids 121 and 238 of Human EPCR.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
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Protein Aliases: Activated protein C receptor; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle; cell cycle, centrosome-associated protein; Centrocyclin; Centrosomal protein CCD41; centrosome-associated protein; Endothelial cell protein C receptor; Endothelial protein C receptor; EPCR; protein C receptor, endothelial
Gene Aliases: AI325044; CCCA; CCD41; EPCR; PROCR