In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human (100%) Marmoset (87%).
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. The intronless GPR32 gene encodes an orphan G protein-coupled receptor that binds to resolvin D1 and lipoxin A4. Resolvin D1 binding to GPR32 has been linked to resolution of pulmonary inflammation, suppression of TGFbeta induced epithelial mesenchymal transition of A549 lung cancer cells. Resolvins are being evaluated as new drug candidates acting at the resolution phase of chronic inflammation.
Protein Aliases: GPCRW; Probable G-protein coupled receptor 32; resolvin D1 receptor; RVDR
Gene Aliases: GPR32; RVDR1
UniProt ID: (Human) O75388
Entrez Gene ID: (Human) 2854