Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Panda, Horse (94%) Rat, Bovine, Elephant (88%) Mouse, Dog (81%).
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
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Protein Aliases: 5-HT-5; 5-HT-5A; 5-HT5A; 5-HT5a receptor; 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; 5-hydroxytryptamine receptor 5A; 5-hydroxytryptamine5a; HTR5A; Serotonin 5-HT5a receptor; Serotonin 5a receptor; Serotonin receptor 5A
Gene Aliases: 5-HT5A; HTR5A
UniProt ID: (Human) P47898
Entrez Gene ID: (Human) 3361