Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Rabbit (89%).
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes.
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Protein Aliases: FFAR; Free fatty acid receptor 1; G protein-coupled receptor 40; G-protein coupled receptor 40; HGNC:4498
Gene Aliases: FFA1R; FFAR1; GPCR40; GPR40
UniProt ID: (Human) O14842
Entrez Gene ID: (Human) 2864