Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla (100%) Monkey, Horse (94%) Gibbon, Dog, Rabbit (88%) Elephant (82%).
This is one of the several different receptors for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT-6; 5-HT6; 5-HT6 receptor; 5-HT6 serotonin receptor; 5-HT6R; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; 5-hydroxytryptamine 6 receptor; 5-hydroxytryptamine receptor 6; HTR6; Serotonin 5-HT-6 receptor; Serotonin 6 receptor; Serotonin receptor 6; Serotonin type 6 receptor
Gene Aliases: 5-HT6; 5-HT6R; HTR6
UniProt ID: (Human) P50406
Entrez Gene ID: (Human) 3362