Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (94%).
GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) and acts as a high affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibits cAMP accumulation.
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Protein Aliases: G protein-coupled receptor 100; G-protein coupled receptor 100; G-protein coupled receptor GPCR142; GPCR142; GPR100; Insulin-like peptide INSL5 receptor; JEG62; Relaxin 3 receptor 2; Relaxin family peptide receptor 4; Relaxin-3 receptor 2; relaxin/insulin-like family peptide receptor 4; RLN3 receptor 2; RLN3R2; RXFP4; RXFPR4
Gene Aliases: GPCR142; GPR100; RLN3R2; RXFP4; RXFPR4
UniProt ID: (Human) Q8TDU9
Entrez Gene ID: (Human) 339403