This antibody is predicted to react with mouse and rat based on sequence homology.
ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, this protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling.
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Protein Aliases: Abelson interactor 1; Abi-1; ABI1; Abl interactor 1; Abl-binding protein 4; abl-interactor 1; Abl-interactor protein 1 long; AblBP4; e3B1; Eps8 SH3 domain-binding protein; Eps8-binding protein; interactor protein AblBP4; nap1 binding protein; Nap1-binding protein; Nap1BP; Spectrin SH3 domain-binding protein 1; SSH3BP1
Gene Aliases: ABI-1; ABI1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1
UniProt ID: (Human) Q8IZP0
Entrez Gene ID: (Human) 10006