Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: HepG2 WCE and NE.
Predicted reactivity: Mouse (97%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeo box 2A; homeo box B5; Homeobox protein HHO.C10; Homeobox protein Hox-2A; Homeobox protein Hox-B5; Homeobox protein Hu-1
Gene Aliases: HHO.C10; HOX2; Hox2.1; HOX2A; HOXB5; HU-1
UniProt ID: (Human) P09067
Entrez Gene ID: (Human) 3215
Molecular Function: helix-turn-helix transcription factor homeodomain transcription factor DNA-binding transcription factor gene-specific transcriptional regulator
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