This antibody detects endogenous protein at a molecular weight of 44 kDa.
Purity is >95% by SDS-PAGE.
E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an "active" E2F transcriptional regulatory complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E2F transcription factor 4, p107/p130-binding; E2F transcription factor 5, p130-binding; E2F-4; E2F-5; p107/p130-binding protein; Transcription factor E2F4; Transcription factor E2F5
Gene Aliases: 2010111M04Rik; AI427446; AU024671; E2F-4; E2F-5; E2F4; E2F5