This antibody detects endogenous protein at a molecular weight of 79 kDa.
Purity is >95% by SDS-PAGE.
As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH-null mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-trans-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase; ECHD; Enoyl-CoA hydratase/3; Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase; L-3-hydroxyacyl-CoA dehydrogenase; L-bifunctional enzyme; L-bifunctional protein, peroxisomal; L-specific bifunctional protein; L-specific multifunctional beta-oxdiation protein; multifunctional enzyme type 1; PBE; PBFE; Peroxisomal bifunctional enzyme; peroxisomal bifunctional enzyme type 1; peroxisomal enoyl-CoA hydratase
Gene Aliases: ECHD; EHHADH; HD; LBFP; LBP; MEF; Mfe; MFP; Pbe; PBFE; 1; 1300002P22Rik; FRTS3; L-PBE; Mfe1; MFP1; perMFE-1