A suggested positive control for Western blot is mouse heart cells; suggested positive control for IHC is human breast carcinoma.
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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Protein Aliases: 18 kDa phosphoprotein; CFL-1; cofilin 1 (non-muscle); cofilin 2 (muscle); Cofilin, muscle isoform; Cofilin, non-muscle isoform; Cofilin-1; Cofilin-2; Cofilin1; epididymis secretory protein Li 15; nemaline myopathy type 7; p18
Gene Aliases: AA959946; CFL; CFL1; CFL2; Cof; cofilin; HEL-S-15; n-cofilin; NEM7