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Invitrogen
A recommended positive control is human small intestine tissue lysate.
At least three isoforms of IL-1RL2 are known to exist; this antibody will detect all three isoforms. IL-1RL2 antibody is not expected to cross-react with IL-1R or IL-1RL1.
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IL-1 receptor-related protein 2; IL-1Rrp2; IL-36 receptor; IL-36R; IL1R-rp2; interleukin 1 receptor-like 2; interleukin-1 receptor related protein 2; Interleukin-1 receptor-like 2; Interleukin-1 receptor-related protein 2
Gene Aliases: AI481289; AW551444; IL-1Rrp2; IL-36R; IL1R-rp2; IL1RL2; IL1RRP2
UniProt ID: (Human) Q9HB29, (Rat) Q62929, (Mouse) Q9ERS7
Entrez Gene ID: (Human) 8808, (Rat) 171106, (Mouse) 107527
Molecular Function: transmembrane signal receptor
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