N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
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Protein Aliases: GluN2A; GluN2B; GluRepsilon1; GluRepsilon2; Glutamate [NMDA] receptor subunit epsilon 2 precursor; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; Glutamate NMDA receptor subunit epsilon-1; Glutamate receptor ionotropic NMDA 2A; Glutamate receptor ionotropic, NMDA 2A; Glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; glutamate receptor, ionotropic, NMDA2B; Grin2a; GRIN2B; hNR3; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2A; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2A; N-methyl-D-aspartate receptor subunit 3; N-Methyl-D-Aspartate Receptor Type 2A; NMDAR2A; NMDAR2B; NMDE2; NME2; NR2A; NR2B; NR3
Gene Aliases: AW490526; EIEE27; EPND; FESD; GluN2A; GluN2B; GRIN2A; GRIN2B; hNR3; LKS; MRD6; NMDAR2A; NMDAR2B; NR2A; NR2B