This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009].
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Protein Aliases: 1-acylglycerol-3-phosphate O-acyltransferase 11; 1-acylglycerophosphocholine O-acyltransferase; 1-AGP acyltransferase 11; 1-AGPAT 11; 1-alkylglycerophosphocholine O-acetyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyl-CoA:lysophosphatidylcholine acyltransferase 2; acyl-CoA:lysophosphatidylcholine acyltransferase member 1; acyltransferase like 1; acyltransferase like 1A; Acyltransferase-like 1; acyltransferase-like 1-A; Aytl1; Aytl1a; LPAAT-alpha; LPC acyltransferase 2; LPCAT-2; Lpcat2a; lyso-PAF acetyltransferase; lyso-platelet-activating factor (PAF) acetyltransferase; lysoPAFAT; lysoPAFAT/LPCAT2; lysoPC acyltransferase 2; Lysophosphatidic acid acyltransferase alpha; Lysophosphatidylcholine acyltransferase 2
Gene Aliases: A330042H22; AGPAT11; AYTL1; Aytl1a; lpafat1; LPCAT-2; LPCAT2; Lpcat2a; LysoPAFAT; RGD1563994